What is QSant™?

QSant™ is a needle free urine test that is collected at home to reduce exposure to COVID. This test provides a comprehensive assessment of kidney health and has the ability to rule in and rule out acute rejection to avoid invasive biopsies.

Which urine markers are being studied?

The urine sample kit evaluates six kidney-specific biomarkers. Studies have shown these markers to accurate predictors of kidney transplant rejection. (Studies: MDPI, MDM)

What is the efficacy of the data (sensitivity/specificity)?

QSant™ rules in and rules out active rejection with >95% sensitivity and specificity. The QScore™ above 32 correlates with the severity of rejection injury (inflammation and tubulitis in the transplant kidney), and can be used repeatedly to assess evolution and resolution of rejection over time.

Can you differentiate transplant rejection versus other kidney diseases?

Currently, QSant™ does not differentiate between cellular rejection versus antibody rejection in kidney transplant recipients as it is designed to pick up all rejection episodes, irrespective of the type of rejection. Together with the QScore™ for rejection risk, we will also provide a general risk for urinary tract infections and diabetes. We will also provide quantification of proteinuria.

How do I order these tests?

You can order tests for your patients via an external portal (ATLAS) or by faxing in a Test Requisition Form to our secure number 628-239-3551. Once the order is received, we will initiate the shipment of the sample kit directly to your patient. Each patient will be assigned a transplant account specialist to coordinate this. We will provide access to the ATLAS portal as well as these test requisition forms. We will work with each transplant center to enable direct QSant™ orders via their respective electronic medical records (EMR) system.

What is turn around time?

After a patient ships the urine samples back to our lab, results will be generated and you will receive a comprehensive test report in 3 business days.

How do I get the reports?

We have several paths to meet the needs of the clinician depending on their preference. Reports will be available in the QSant™ clinician portal, in an EMR interface, or by a secured fax.

Who can I discuss the reports with – is there a medical liaison?

We have medical personnel on staff including a medical director and medical science liaisons that can speak with clinicians regarding interpretation of the reports and any other scientific medical questions. Please call 1-833-MyQSANT to set up a call.

How often are samples being collected?

The frequency of sample collection is determined by the clinician, based on the patient’s medical history. For example, testing can be done 7 times a year in the first post-transplant year and then 4 times a year every year thereafter. However, the frequency can vary amongst each patient as determined by the transplant physician. We anticipate that by consistently testing and closely monitoring kidney health over time, you can adjust treatment response based on the QSant™ test results.

Do you have ongoing research studies or registry studies?

Yes, we can work with interested clinicians in a number of ways. These include site-specific investigational studies as well as a larger registry to reinforce clinical utility of the test. If interested please contact 1-833-MyQSANT.